how much lycopene per day

One study of a specific lycopene supplement (LycoRed) suggested that taking lycopene 2 mg daily starting at 12-20 weeks of pregnancy and continuing until delivery might increase the rates of … 2010;64(10):1235-1238. Hsing, A. W., Comstock, G. W., Abbey, H., and Polk, B. F. Serologic precursors of cancer. Tavani, A., Longoni, E., Bosetti, C., Maso, L. D., Polesel, J., Montella, M., Ramazzotti, V., Negri, E., Franceschi, S., and La Vecchia, C. Intake of selected micronutrients and the risk of surgically treated benign prostatic hyperplasia: a case-control study from Italy. View abstract. Dietary lycopene: its properties and anticarcinogenic effects. View abstract. However, other research found no link between lycopene intake in the diet and the development of an enlarged prostate. Nutr Cancer. Parfitt, V. J., Rubba, P., Bolton, C., Marotta, G., Hartog, M., and Mancini, M. A comparison of antioxidant status and free radical peroxidation of plasma lipoproteins in healthy young persons from Naples and Bristol. Rowles JL 3rd, Ranard KM, Smith JW, An R, Erdman JW Jr. 2003;81(3):257-262. J Nutr 1997;127(8 Suppl):1636S-45S. Bohm, F., Tinkler, J. H., and Truscott, T. G. Carotenoids protect against cell membrane damage by the nitrogen dioxide radical. View abstract. Response of hormone refractory prostate cancer to lycopene. Eichler, O., Sies, H., and Stahl, W. Divergent optimum levels of lycopene, beta-carotene and lutein protecting against UVB irradiation in human fibroblastst. View abstract. 2008;(4):CD007156. Colditz, G. A., Branch, L. G., Lipnick, R. J., Willett, W. C., Rosner, B., Posner, B. M., and Hennekens, C. H. Increased green and yellow vegetable intake and lowered cancer deaths in an elderly population. Br.J Cancer 1979;39(3):293-309. J Agric Food Chem 2-21-2007;55(4):1597-1603. Sakamoto H, Mori H Ojima F et al. Mannisto, S., Yaun, S. S., Hunter, D. J., Spiegelman, D., Adami, H. O., Albanes, D., van den Brandt, P. A., Buring, J. E., Cerhan, J. R., Colditz, G. A., Freudenheim, J. L., Fuchs, C. S., Giovannucci, E., Goldbohm, R. A., Harnack, L., Leitzmann, M., McCullough, M. L., Miller, A. View abstract. 2016;116(12):2091-2096. Relationships of serum carotenoids, retinol, alpha-tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States). View abstract. BMJ 10-13-2007;335(7623):755. Research on the effect of lycopene for preventing high blood pressure during pregnancy is unclear. 11-1-1989;49(21):6144-6148. J.Am.Diet.Assoc. Proc.Soc.Exp.Biol.Med 1998;218(2):121-124. Di Giacomo, C., Acquaviva, R., Sorrenti, V., Vanella, A., Grasso, S., Barcellona, M. L., Galvano, F., Vanella, L., and Renis, M. Oxidative and antioxidant status in plasma of runners: effect of oral supplementation with natural antioxidants. Systemic and skin-targeting beneficial effects of lycopene-enriched ice cream: A pilot study. View abstract. Tomato sauces, pastes, soups and juices contain more lycopene than the fresh vegetable. Corridan BM, O'Donoghue M, Hughes DA, and et al. Cancer Epidemiol.Biomarkers Prev. Hardening of the arteries (atherosclerosis). 2008;88(2):372-383. However, research has not confirmed that lycopene offers greater preventive benefits than potassium, vitamin C or other nutrients found in these foods. Am.J.Epidemiol. Linus Pauling Institute at Oregon State University: Micronutrient Information Center: Carotenoids, Centers for Disease Control and Prevention: Fruits & Vegetable Benefits: Color Guide, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. View abstract. Kristal, A. R., Till, C., Platz, E. A., Song, X., King, I. Am J Epidemiol. pii: E950. Cancer Res 2-1-1993;53(3):536-543. Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer. Am J Epidemiol 2000;151:119-23. (Phila) 2011;4(5):711-718. Lycopene that comes from food sources has no set recommended intake amount. View abstract. J Cell Biochem Suppl 1995;22:236-246. Steinmetz, K. A., Potter, J. D., and Folsom, A. R. Vegetables, fruit, and lung cancer in the Iowa Women's Health Study. Holick, C. N., Michaud, D. S., Stolzenberg-Solomon, R., Mayne, S. T., Pietinen, P., Taylor, P. R., Virtamo, J., and Albanes, D. Dietary carotenoids, serum beta-carotene, and retinol and risk of lung cancer in the alpha-tocopherol, beta-carotene cohort study. A sexually transmitted infection that can lead to genital warts or cancer (human papillomavirus or HPV). Int J Epidemiol. Levi, F., La Vecchia, C., Gulie, C., and Negri, E. Dietary factors and breast cancer risk in Vaud, Switzerland. Grainger, E. M., Schwartz, S. J., Wang, S., Unlu, N. Z., Boileau, T. W., Ferketich, A. K., Monk, J. P., Gong, M. C., Bahnson, R. R., DeGroff, V. L., and Clinton, S. K. A combination of tomato and soy products for men with recurring prostate cancer and rising prostate specific antigen. View abstract. Indian J Pharmacol 2016;48:26-31. Comparative analysis of lycopene in oxidative stress. Am J Epidemiol. Inverse associations between plasma lycopene and other carotenoids and prostate cancer. Gianetti, J., Pedrinelli, R., Petrucci, R., Lazzerini, G., De Caterina, M., Bellomo, G., and De Caterina, R. Inverse association between carotid intima-media thickness and the antioxidant lycopene in atherosclerosis. Because I don’t eat a diet that high in tomato paste, it is convenient for me to take it as a supplement, and I can afford it. In addition, there is no daily recommended value for lycopene; that said, studies suggest that intakes between 8-21 mg per day appear to be the most beneficial, Healthline reports. Riboli, E., Gonzalez, C. A., Lopez-Abente, G., Errezola, M., Izarzugaza, I., Escolar, A., Nebot, M., Hemon, B., and Agudo, A. View abstract. Another meta-study(4) in 2013 showed that taking greater than 12 mg of lycopene per day almost certainly could reduce hypertension and SBD. Jarvinen, R., Knekt, P., Seppanen, R., and Teppo, L. Diet and breast cancer risk in a cohort of Finnish women. Mangels, A. R., Holden, J. M., Beecher, G. R., Forman, M. R., and Lanza, E. Carotenoid content of fruits and vegetables: an evaluation of analytic data. A., Meyer-Wenger, A., Moser, U., Wright, A., Southon, S., Thurnham, D., Chopra, M., van den, Berg H., Olmedilla, B., Favier, A. E., and Roussel, A. M. No significant effects of lutein, lycopene or beta-carotene supplementation on biological markers of oxidative stress and LDL oxidizability in healthy adult subjects. View abstract. View abstract. Franceschi, S., Bidoli, E., La Vecchia, C., Talamini, R., D'Avanzo, B., and Negri, E. Tomatoes and risk of digestive-tract cancers. Boileau TW, Liao Z, Kim S, et al. View abstract. View abstract. Cancer Epidemiol Biomarkers Prev 2005;14:1074-81. J Nutr 2001;131(8):2096-2100. A., and Lopez-Andreu, J. 1991;20(3):603-610. View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: Eur.J.Clin.Nutr. Aim for 22 mg of lycopene a day, which is about eight red cherry tomatoes or a glass of tomato juice. J Natl Cancer Inst 1996;88:340-8.. View abstract. View abstract. J Nutr 1997;127:1833-7. Nishimura M, Tominaga N, Ishikawa-Takano Y, Maeda-Yamamoto M, Nishihira J. 1992;21(3):437-441. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. 9-15-2002;156(6):536-547. View abstract. Hozawa, A., Jacobs, D. R., Jr., Steffes, M. W., Gross, M. D., Steffen, L. M., and Lee, D. H. Circulating carotenoid concentrations and incident hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Kristenson, M., Zieden, B., Kucinskiene, Z., Elinder, L. S., Bergdahl, B., Elwing, B., Abaravicius, A., Razinkoviene, L., Calkauskas, H., and Olsson, A. G. Antioxidant state and mortality from coronary heart disease in Lithuanian and Swedish men: concomitant cross sectional study of men aged 50. Cancer of the cervix. Johnson, E. J. View abstract. Some research suggests that increasing lycopene consumption in the diet, or having higher lycopene blood levels, is linked with a lower risk of prostate cancer. View abstract. J Natl.Cancer Inst. Nutr Cancer 2008;60(2):145-154. View abstract. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. View abstract. View abstract. Am J Clin Nutr 1992;55(6):1120-5. NCC Carotenoid Database for U.S. Foods. J.Biol.Regul.Homeost.Agents 2011;25(3):435-441. However, other research suggests that lycopene does not affect blood pressure during pregnancy. Watermelon provides about 12.7 grams of lycopene per 2 cup serving. Neuman I, Nahum H, Ben-Amotz A. View abstract. J Assoc Physicians India 2012;60:17-19. Forbes K, Gillette K, Sehgal I. Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication. View abstract. Perabo, F. G., von Low, E. C., Siener, R., Ellinger, J., Muller, S. C., and Bastian, P. J. View abstract. Am J Clin Nutr 1998;68(2):319-327. There is currently no recommended daily intake for lycopene. J Nutr 2001;131(5):1449-1451. Am.J.Clin.Nutr. White patches inside the mouth that are usually caused by smoking (oral leukoplakia). Anne Tourney specializes in health and nutrition topics. View abstract. Paterson, E., Gordon, M. H., Niwat, C., George, T. W., Parr, L., Waroonphan, S., and Lovegrove, J. Belcaro G, Cesarone MR, Cornelli U, et al. Zhang S, Hunter DJ, Forman MR, et al. Intake of carotenoids and retinol in relation to risk of prostate cancer. Potischman, N., McCulloch, C. E., Byers, T., Nemoto, T., Stubbe, N., Milch, R., Parker, R., Rasmussen, K. M., Root, M., Graham, S., and . Freudenheim, J. L., Graham, S., Marshall, J. R., Haughey, B. P., and Wilkinson, G. A case-control study of diet and rectal cancer in western New York. Lu QY, Hung JC, Heber D, et al. Ingestion by men of a combined dose of beta-carotene and lycopene does not affect the absorption of beta-carotene but improves that of lycopene. Clinton SK, Emenhiser C, Giovannucci EL, and et al. Sedjo RL, Papenfuss MR, Craft NE, Guiliano AR. Early research shows that taking lycopene by mouth daily for 3 months improves sperm quality in some men with fertility problems due to unknown causes. View abstract. View abstract. Although lycopene may offer numerous health benefits, a recommended intake for this plant pigment has not been established. A., Martin, F. L., Morris, J. D., and Muir, G. H. Lycopene inhibits DNA synthesis in primary prostate epithelial cells in vitro and its administration is associated with a reduced prostate-specific antigen velocity in a phase II clinical study. 2008;42(1):94-102. Plasma retinol and plasma and lipoprotein tocopherol and carotenoid concentrations in healthy elderly participants of the Framingham Heart Study. View abstract. A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men. It's unclear if this benefit is due to lycopene, other ingredients, or the combination. View abstract. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. any of the products or services that are advertised on the web site. Zhang, S., Tang, G., Russell, R. M., Mayzel, K. A., Stampfer, M. J., Willett, W. C., and Hunter, D. J. How much lycopene is too much? Stahl, W., Heinrich, U., Wiseman, S., Eichler, O., Sies, H., and Tronnier, H. Dietary tomato paste protects against ultraviolet light-induced erythema in humans. Burri, B. J., Neidlinger, T. R., and Clifford, A. J. Serum carotenoid depletion follows first-order kinetics in healthy adult women fed naturally low carotenoid diets. Carroll, Y. L., Corridan, B. M., and Morrissey, P. A. Lipoprotein carotenoid profiles and the susceptibility of low density lipoprotein to oxidative modification in healthy elderly volunteers. Kidney cancer. 2017;257:100-108. BMC.Complement Altern.Med. Le Marchand, L., Yoshizawa, C. N., Kolonel, L. N., Hankin, J. H., and Goodman, M. T. Vegetable consumption and lung cancer risk: a population-based case- control study in Hawaii. Diabetes Care 2004;27:362-6. View abstract. A., and Guymer, R. H. Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. Cancer Res. High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). The standard serving size of Lycopene is 200 mg once or twice a day unless a physician recommends otherwise. Uncontrolled Blood Sugar: How Dangerous Is It? 2008;99(1):137-146. Cancer Epidemiol Biomarkers Prev 2001;10:749-56. Proc.Soc.Exp.Biol.Med 1998;218(2):129-139. 12-21-1988;80(20):1620-1625. Ophthalmology 2002;109(12):2272-2278. Offord, E. A., Gautier, J. C., Avanti, O., Scaletta, C., Runge, F., Kramer, K., and Applegate, L. A. Photoprotective potential of lycopene, beta-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin fibroblasts. Am J Clin Nutr 2004;79:47-53. View abstract. Prostate Cancer Prostatic.Dis. View abstract. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Klipstein-Grobusch K, Launer LJ, Geleijnse JM, et al. View abstract. J.Agric.Food Chem. J Am Coll Nutr 1995;14(6):614-20. View abstract. Breast cancer and dietary and plasma concentrations of carotenoids and vitamin A. J Natl Cancer Inst 2003;95:1563-5. VanEenwyk, J., Davis, F. G., and Bowen, P. E. Dietary and serum carotenoids and cervical intraepithelial neoplasia. Skin rash caused by sun exposure (polymorphous light eruption or PMLE). Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Centonze, S., Boeing, H., Leoci, C., Guerra, V., and Misciagna, G. Dietary habits and colorectal cancer in a low-risk area. Clinical research has not verified that taking lycopene in supplement form can reduce your risk of cancer or heart disease. Diabetes Care 2000;23(6):733-738. Stahl, W. and Sies, H. Lycopene: a biologically important carotenoid for humans? Porrini, M., Riso, P., and Oriani, G. Spinach and tomato consumption increases lymphocyte DNA resistance to oxidative stress but this is not related to cell carotenoid concentrations. J Photochem.Photobiol.B 1994;26(3):283-285. View abstract. Cancer Causes Control 2003;14:319-26. View abstract. Cancer 8-1-1989;64(3):598-604. Ziegler, R. G. Vegetables, fruits, and carotenoids and the risk of cancer. Serologic indicators. Effects of lycopene-enriched tomato oleoresin on 7,12-dimethyl- benz[a]anthracene-induced rat mammary tumors. B., Rohan, T. E., Schatzkin, A., Virtamo, J., Willett, W. C., Wolk, A., Zhang, S. M., and Smith-Warner, S. A. Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies. Low-dose supplementation with lycopene or beta-carotene does not enhance cell-mediated immunity in healthy free-living elderly humans. But diets specifically rich in lycopene alone don't seem to be linked with a lower risk of ALS. The effects of dietary lycopene supplementation on human seminal plasma. View abstract. Oral Oncol. We currently have no information for LYCOPENE Interactions. Comp Rev Food Sci Food Safety 2008;7:255-70. Oral Oncol 2004;40:591-6. According to MayoClinic.com, recommended doses of lycopene generally range from 2 to 30 mg per day for up to six months. Dherani, M., Murthy, G. V., Gupta, S. K., Young, I. S., Maraini, G., Camparini, M., Price, G. M., John, N., Chakravarthy, U., and Fletcher, A. E. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. View abstract. 2014;42(1):25-38. Use of this web site constitutes acceptance of the LIVESTRONG.COM Oral Oncol 2012;48(5):393-398. View abstract. J Am Coll Nutr 2001;20(3):232-238. 1991;20(2):362-367. Shi, J. and Le Maguer, M. Lycopene in tomatoes: chemical and physical properties affected by food processing. Am J Clin Nutr 2000;71:575-82. J Am Coll.Nutr 1997;16(2):109-126. Dietary antioxidant intake and incidence of early age-related maculopathy. View abstract. Baghurst, P. A., McMichael, A. J., Slavotinek, A. H., Baghurst, K. I., Boyle, P., and Walker, A. M. A case-control study of diet and cancer of the pancreas. Mol.Nutr.Food Res. Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. View abstract. Rao AV, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Lyle, B. J., Mares-Perlman, J. Int J Cancer 11-1-2006;119(9):2148-2154. Atherosclerosis 2000;148:49-56. View abstract. Lycopene is a carotenoid and natural pigment that gives some vegetables and fruits their color. View abstract. View abstract. 1997;6(8):617-623. Ribaya-Mercado JD, Ordovas JM, Russell RM. Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. 2004;58(10):1350-1358. [A critical assessment of phytotherapy for prostate cancer]. Unlu, N. Z., Bohn, T., Francis, D. M., Nagaraja, H. N., Clinton, S. K., and Schwartz, S. J. Lycopene from heat-induced cis-isomer-rich tomato sauce is more bioavailable than from all-trans-rich tomato sauce in human subjects. View abstract. Hughes, D. A., Wright, A. J., Finglas, P. M., Polley, A. C., Bailey, A. L., Astley, S. B., and Southon, S. Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers. 2019;11(5). Chernyshova MP, Pristenskiy DV, Lozbiakova MV, Chalyk NE, Bandaletova TY, Petyaev IM. 7-15-1991;134(2):167-179. View abstract. Some early research shows that a diet high in lycopene, primarily from tomatoes, seems to lower the risk of developing pancreatic cancer. View abstract. Am J Epidemiol 1997;146:618-26. A prospective study of tomato products, lycopene, and prostate cancer risk. Asian Pac J Cancer Prev. Watzl, B., Kulling, S. E., Moseneder, J., Barth, S. W., and Bub, A. Results from a population-based case-control study in southern Italy. View abstract. Early research shows that taking lycopene by mouth for 3 months does not improve the response to radiotherapy and chemotherapy in people with brain tumors. Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis. View abstract. 2009;40(1):37-43. Chen J, Song Y, Zhang L. Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies. Story EN, Kopec RE, Schwartz SJ, Harris GK. Cancer Causes Control 1998;9(1):89-97. Isr.Med.Assoc.J. Br J Nutr 2005;93(3):291-297. J Natl Cancer Inst 1999;91:547-56. Ziegler, R. G., Mason, T. J., Stemhagen, A., Hoover, R., Schoenberg, J. Franceschi, S., Favero, A., La Vecchia, C., Negri, E., Conti, E., Montella, M., Giacosa, A., Nanni, O., and Decarli, A. Eye Disease Case-Control Study Group. View abstract. Urology 2007;69(2):289-294. View abstract. View abstract. Ried, K., Frank, O. R., and Stocks, N. P. Dark chocolate or tomato extract for prehypertension: a randomised controlled trial. Helzlsouer, K. J., Comstock, G. W., and Morris, J. S. Selenium, lycopene, alpha-tocopherol, beta-carotene, retinol, and subsequent bladder cancer. Am J Epidemiol. View abstract. ) 2003 ; 133 ( 1 ):98-101 registered nurse with experience in medical-surgical nursing, health... Apricots and other carotenoids as antioxidants adding a regular supplement to your diet and Wald, N., Riso P.... Oxidative stress increased protective serum antioxidants and primary prevention of chronic diseases and Koff W.. Heart failure growth how much lycopene per day normal human prostate LDL resistance to oxidation you the most for. Doctor about any health conditions before taking lycopene in their diet have a lower risk of developing prostate Prostatic.Dis! J cancer 6-19-1991 ; 48 ( 3 ):213-221 for the treatment of high-grade prostate intraepithelial neoplasia Bjelke! O., Garcia-Castell, J. 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